Advantages | Disadvantages |
Cold knife conization |
| Technical simplicity | General or regional anesthetic required |
| Excellent specimen quality | Distortion after healing |
| | Complication rate higher |
Laser conization |
| Good specimen quality | Technically difficult |
| Good hemostasis | Expense and upkeep of equipment |
| Healing with minimal distortion | Some thermal damage |
| Low complication rate | A narrow deep cone is difficult |
| Can be done in an office setting | |
| Flexible treatment of endocervix |
Large loop excision of the transformation zone |
| Easily done in the office setting | Some thermal damage |
| Rapid performance | A large or deep cone may be difficult to perform in the office and result in more thermal damage if a second loop excision is required |
| Technically easy | |
| Equipment inexpensive |
| Low complication rate |
| Good specimen quality |
| Healing with minimal distortion |